Aptagen, LLC
R12-A-R12 (Bovine PrP) (ID# 10147)
RNA
Bovine PrP (Prion Protein)
Protein
500 nM (reported value)
10 mM K-phosphate (pH 6.2) and 100 mM KCl
Heated at 95 °C for 5 min, quickly cooled on ice, and then stored at 4 °C
This is a self-dimer of the related aptamer R12
5'-rGprGprAprGprGprAprGprGprAprGprGprAprAprGprGprAprGprGprAprGprGprAprGprGprAp-3'
25
8024.2 g/mole
281100 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Mashima, T., Lee, JH., Kamatari, Y.O. et al. Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein. Sci Rep 10, 4934 (2020). https://doi.org/10.1038/s41598-020-61966-4
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