(R)-Ibuprofen (IBA2) Aptamer Details

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(R)-Ibuprofen (IBA2) (ID# 10039)

DNA
(R)-Ibuprofen
Other
3 µM (reported value)
100 mM NaCl, 20 mM Tris–HCl, 2 mM MgCl2, 5 mM KCl, 1 mM CaCl2, 0.02% Tween 20, pH 7.6
Room temperature°C
Heated to 90°C for 10 min, cooled to 4°C for 15 min, incubated at room temperature for 8 min
Specifically binds to ibuprofen over fenoprofen, flubiprofen, naproxen, and antibiotics of oxytetracycline
76
23679.3 g/mole
755800 L/(mole·cm)

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Yeon Seok Kim, Chang Jun Hyun, In Ae Kim, Man Bock Gu, Isolation and characterization of enantioselective DNA aptamers for ibuprofen, Bioorganic & Medicinal Chemistry, Volume 18, Issue 10, 2010, Pages 3467-3473, ISSN 0968-0896, https://doi.org/10.1016/j.bmc.2010.03.074.

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