Co-M8 (Cobalt Ion) Aptamer Details

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Co-M8 (Cobalt Ion) (ID# 9923)

DNA
Cobalt Ion (Co2+)
Other
187±3.7 µM (reported value)
50mM HEPES, 100mM NaCl, 0.025% Tween-20, pH 7.5
Room Temperature°C
Heated to 95 C for 10 minutes, cooled on ice for 10 minutes, placed at room temperature for 10 minutes
Specific against other counter-selected metal ions (Mn2+,Cu2+,Ca2+,Al3+, Ba2+,Cd2+,Ni2+,Zn2+,Ce3+,Pb2+,Cr3+,Fe3+ and Hg2+) except Hg2+ which non-specifically binds to thymine bases.
Magnetically tunable. Effective binding is achieved only when a magnetic field of 6T or greater is applied.
80
24546.9 g/mole
748300 L/(mole·cm)

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Gao, S., Wang, L., Yao, L. et al. Aptamers with magnetically tunable affinity for divalent cobalt ions. Nat Commun 17, 4150 (2026). https://doi.org/10.1038/s41467-026-70871-9

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