Aptagen, LLC
Co-M3 (Cobalt Ion) (ID# 9930)
DNA
Cobalt Ion (Co2+)
Other
48.7±0.4 µM (reported value)
50mM HEPES, 100mM NaCl, 0.025% Tween-20, pH
7.5
27°C
Heated to 95 C for 10 minutes, cooled on ice for 10 minutes, placed at room temperature for 10 minutes
Specific against other metal ions except mercury, which non-specifically binds to thymine
This aptamer is magnetically tunable, meaning the above affinity is only reached in a magnetic field of 9T. Other measured Kd values are 80.1±2.4 µM at 6T, 128±2.2 µM at 3T, and 171±1.5 µM at ambient conditions.
dTpdApdCpdApdCpdTpdGpdCpdApdCpdTpdGpdCpdGpdTpdTpdApdGpdApdGpdGpdTpdTpdApdCpdGpdGpdCpdCpdCpdCpdTpdGpdCpdTpdCpdApdGpdCpdApdCpdApdGpdCpdTpdCpdCpdTpdTpdTpdApdTpdGpdGpdTpdApdTpdApdCpdGpdApdTpdGpdGpdApdCpdGpdTpdGpdTpdCpdApdCpdApdGpdTpdApdCpdTpdGp
80
24596.9 g/mole
752500 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Gao, S., Wang, L., Yao, L. et al. Aptamers with magnetically tunable affinity for divalent cobalt ions. Nat Commun 17, 4150 (2026). https://doi.org/10.1038/s41467-026-70871-9
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