Aptagen, LLC
RNA
Anti-NF-kB p65
Protein
149 nM (reported value)
Selection buffer: 10mM HEPES at pH 7.5, 100mM NaCl, 1mM DTT
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Binds to both p65 and p50, with kd of 149nM and 190nM respectively.
Anti-NF-kB p65 (D1) (ID# 389)
5'rGprCprAprUprGprCprAprGprUprGprUprCprUprAprUprUprCprUprCprGprAprGprUprAprGprCprGprAprUprCprGprUprUprGprAprAprGprGprGprGprUprAprUprAprAprGprGprUprUprGprGprCprAprGprAprUprCprGprCprUprAprGprCprAprUprGprCprAprAprCprUprGprAprCprUprCprGprGprAprUprAprAprGprCprAp3'
85
27468.57 g/mole
858400 L/(mole·cm)
49.41%
1.16
32.00
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Wurster, S. E, and Maher, L. J. "Selection and characterization of anti-NF-kB p65 aptamers." RNA, 14(2008): 1037-1047.
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