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Apta-Index™: ErbB2 (SE15-8) (ID# 202)

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ErbB2 (SE15-8) (ID# 202)

ErbB2 (SE15-8)
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
2'-F-RNA ErbB2 in Breast Cancer Cells Protein 3.49 nM (reported value) Binding buffer: 20 mM HEPES (pH 7.0), 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, and 40 U RNase Inhibitor N/A If the oligo is a known aptamer sequence: For binding studies, perform a refolding program to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-rAprGpfCpfCprGpfCprGprAprGprGprGprGprAprGprGprGprApfUprAprGprGprGpfUprAprGprGprGpfCprGpfCprGprGpfCpfUp-3'
34 11239.85 g/mole 341100.00 L/(mole·cm) 73.53% 2.93 32.95

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Kim and Jeong. "In Vitro Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells." Oligonucleotides, doi:10.1089/oli.2011.028.

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