Aptamer Details

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WT62 (ID# 8071)

Aptamer Chemistry: DNA

Target: HIV-1 Reverse Transcriptase

Antigen/Target Category: Protein

Affinity (Kd): 7.51±0.29x10^-8 nM (reported value)

Binding Conditions/Buffer: 10 mM HEPES pH 7.5, 150 mM NaCl, 80 mM KCl, and 5 mM MgCl2

Binding Temp: 25°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 41

Molecular Weight: 12687.3

Extinction Coefficient: 412100

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Hannongbua, S., Ratanabunyong, S., Aeksiri, N., Yanaka, S., Yagi-Utsumi, M., Kato, K., & Choowongkomol, K. (2020). Characterization of new DNA Aptamers for anti‐HIV‐1 Reverse Transcriptase. ChemBioChem. doi:10.1002/cbic.202000633

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