Aptamer Details

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Triple-negative breast cancer MDA-MB-231 aptamer (Apt2) (ID# 8538)

Human triple-negative breast cancer cell line MDA-MB-231
17.7 nM (reported value)
1 mM CaCl2·2H2O and 1.5 mM MgCl2·6H2O in 1X PBS, pH 7.4
37 °C°C
Significantly lower binding affinity for all other triple-negative breast cancer lines tested (Hs 578T, MDA-MB-157, MDA-MB-468) compared to MDA-MB-231

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ferreira D, Barbosa J, Sousa DA et al. Selection of aptamers against triple negative breast cancer cells using high throughput sequencing. Sci Rep 11, 8614 (2021). https://doi.org/10.1038/s41598-021-87998-y

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