Aptagen, LLC
TH14 (ID# 9533)
RNA
BACE1-CT
Small Organic
npBACE 360 and 280 nM (reported value)
80.4°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dGpdGpdGpdApdTpdApdGpdGpdApdTpdCpdCpdApdCpdApdTpdCpdTpdApdCpdGpdTpdApdTpdTpdApdCpdGpdCpdApdApdCpdGpdCpdCpdGpdGpdGpdCpdCpdApdCpdTpdApdCpdGpdCpdGpdApdApdTpdGpdGpdCpdApdApdGpdCpdCpdCpdGpdTpdCpdGpdApdCpdTpdTpdCpdApdCpdTpdGpdCpdApdGpdApdCpdTpdTpdGpdApdCpdGpdApdApdGpdCpdTpdTp-3'
90
27692.9 g/mole
856800 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Rentmeister A, A Bill, T Wahle, J Walter and M Famulok. (2006). RNA aptamers selectively modulate protein recruitment to the cytoplasmic domain of b-secretase BACE1 in vitro. RNA 12:1650–1660. DOI: 10.1261/rna.126306
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