Aptamer Details

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TGF-??1 (T18_1_3) (ID# 7475)

Aptamer Chemistry: DNA

Target: Transforming Growth Factor-??1 (TGF-??1)

Antigen/Target Category: Protein

Affinity (Kd): 94 nM (reported value)

Binding Conditions/Buffer: PBS with 1 MgCl₂.

Binding Temp: RT°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 74

Molecular Weight: 23064.62

Extinction Coefficient: 673000

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Kang, Jonghoon, et al. "Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-??1 protein." Bioorganic & Medicinal Chemistry Letters, 18 (2008): 1835-1839.

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