Tetrodotoxin (TTX)-binding Phosphorothioate (PS) Aptamer Aptamer Details

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Tetrodotoxin (TTX)-binding Phosphorothioate (PS) Aptamer (ID# 10141)

DNA
Tetrodotoxin (TTX)
Small Organic
14.3 µM (reported value)
1x Phosphate Buffered Saline (PBS)(154 mM NaCl, 5.6 mM Na2HPO4, 1.1 mM KH2PO4, pH 7.4)
25 °C
Heated to 95°C for 5 minutes, followed by slow cooling to room temperature.
Specific to tetrodotoxin (TTX) over non-selective scrambled Phosphorothioate (PS) aptamer, saxitoxin, and bupivacaine hydrochloride.
30 Base Pairs
9167 g/mole
28,0000 L/(mole·cm)

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Wang, D., Li, Y., Deng, X. et al. An aptamer-based depot system for sustained release of small molecule therapeutics. Nat Commun 14, 2444 (2023). https://doi.org/10.1038/s41467-023-37002-0

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