Aptagen, LLC
TEPP (ID# 8144)
DNA
bEnd.3 and MDA-MB-231
Cells
110-85.6 nM (reported value)
PBS with 1mM MgCl2, 0.1 mg/mL tRNA, 1mg/mL bovine serum albumin, and 10% FCS
37°C
Mfold
BIFUNCTIONAL aptamer. Affinity value is not a range. First value is affinity with bEnd.3, second value is affinity with MDA
5'-dGpdCpdGpdCpdGpdGpdTpdApdCpdCpdGpdCpdGpdCpdTpdApdApdCpdGpdGpdApdGpdGpdTpdTpdGpdCpdGpdTpdCpdCpdGpdTp-3'
33
10266.58
304900
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Macdonald, J., Denoyer, D., Henri, J., Jamieson, A., Burvenich, I. J., Pouliot, N., & Shigdar, S. (2020). Bifunctional aptamer–doxorubicin conjugate crosses the blood–brain barrier and selectively delivers its payload to EpCAM-positive tumor cells. Nucleic acid therapeutics, 30(2), 117-128.
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