Aptamer Details

Back to Search Results

TB-5 Nucleolin Aptamer (ID# 8587)

Nucleolin (NCL)
165.9 nM (reported value)
Dulbecco’s phosphate buffered saline with 4.5 g/L glucose, 5 mM MgCl2, 0.1 mg/mL yeast tRNA, 1 mg/mL BSA
4 °C°C
Recognizes Breast cancer (5637, SW780, MCF-7), Ovarian cancer (Ovcar3), Colon cancer (RKO), Lung cancer (A549), Liver cancer (HepG2). Low recognition of Renal cancer, Stomach cancer.
Does not form G-quadruplex secondary structure. Appears to bind to RRM2 and RRM3.
16020.4 g/mol
487700 L/(mole*cm)

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Y. Liu, B. Hu, X. Pei, J. Li, D. Qi, Y. Xu, H. Ou, Y. Wu, L. Xue, J. H. Huang, E. Wu, X. Hu, A Non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer. Adv. Healthcare Mater. 2023, 12, 2300791. https://doi.org/10.1002/adhm.202300791

Have your aptamer oligo synthesized ORDER