Aptamer Details

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TAT RNA Aptamer TAT-X (ID# 8412)

Recombinant Trans-Activator of Transcription Aptamer binding Protein (RBP-mCherry-RBP)
3.49 nM (reported value)
50 mM Tris-HCl, 50 mM NaCl, 1 mM EDTA, pH 7.4.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Four TAT aptamers were fused together through a specially designed four-way junction and the corresponding RNA transcript was referred to as TAT-X which was produced stably in vivo and readily isolated from RNase III-deficient cells. With specific modification, TAT aptamer can also be conjugated with other aptamers including Spinach 2 to produce more multimeric aptamers with related functions.
204 nt
67.32 kDa

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Zou Z, Younas T, Dumsday G, Haritos VS, He L. Rapid production of multimeric RNA aptamers stabilized by a designed pseudo-circular structure in E. coli. Biotechnol J. 2023 Mar;18(3):e2200390. doi: 10.1002/biot.202200390. Epub 2022 Dec 5. PMID: 36427490.

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