Aptagen, LLC
SECURA-3 (ID# 8082)
RNA
Pituitary tumour transforming gene 1 (PTTG1)
Protein
16.41 ± 6.4 nM (reported value)
20 mM Tris-HCl (pH 8.6), 8 M Urea, 150 mM NaCl, 10% Glycerol, 1.5X Roche Protease Inhibitor Cocktail EDTA-free).
10 mM HEPES-KOH (pH 7.4) and 150 mM NaCl
95, 25°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5’- rGprGprAprGprCprUprCprAprGprCprCprUprUprCprAprCprUprGprCprGprAprUprCprAprCprCprGprUprGprUprCprGprGprUprGprGprCprUprAprGprUprCprGprAprUprGprUprAprUprCprCprCprGprAprUprCprAprCprCprAprUprUprGprGprGprGprGprCprAprAprGprUprUprUprAprGprAprCprAprGprGprCprAprCprCprAprCprGprGprUprCprGprGprAprUprCprCprAprCp -3'
99
30229.1
907400
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Prabu, S. S., Ch’ng, E. S., Woon, P. Y., Chen, J.-H., Tang, T.-H., & Citartan, M. (2020). Unravelling the diagnostic and therapeutic potentialities of a novel RNA aptamer isolated against human pituitary tumour transforming gene 1 (PTTG1) protein. Analytica Chimica Acta. doi:10.1016/j.aca.2020.09.038
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