Aptamer Details

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SE43 (ID# 8191)

Staphylococcus epidermidis
PBS for selection; PBS containing 1% BSA and 0.05% Tween20 for binding assay
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Highly specific to Staphylococcus epidermidis and not specific towards human platelets and plasma
Designed to eliminate bacteria from platelet units to improve the safety of blood transfusions. Aptamer is not DNA, but FNA chemistry.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Kaur SJ, Gilman V, Duong M, Asher DM, Gregori L. Rapid selection of single-stranded DNA aptamers binding Staphylococcus epidermidis in platelet concentrates. Biotechniques. 2018 Dec;65(6):331-338. doi: 10.2144/btn-2018-0081. PMID: 30477331.

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