Aptamer Details

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S22 (ID# 8157)

Aptamer Chemistry: DNA

Target: MUC-1

Antigen/Target Category: Protein

Affinity (Kd): 0.010 - 1000 nM (reported value)

Binding Conditions/Buffer: Bound to a gold electrode in order to transmit aptasensor data.

Binding Temp: 25°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Comments: This aptamer is intended to act as an Electrochemical Aptasenor. In order to function properly, the aptamer needs to be connected to a magnetic bead on the 5' terminus.

Sequence ():

Length: 25

Molecular Weight: 7743

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Wen W., et al. "An insertion approach electrochemical aptasensor for mucin 1 detection based on exonuclease-assisted target recycling." Biosensors and Bioelectronics, 71 (2015): 13–17. doi: https://doi.org/10.1016/j.bios.2015.04.001

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