Aptagen, LLC
RSV aptamer (ID# 9931)
DNA
RSV Glycoprotein
Protein
2.38 nM (reported value)
A capillary electrophoresis system with fluorescence detection (excitation/emission: 488 nm/520 nm) was used. Human Saliva used as a matrix.
25 °C°C
The ssDNA library was heat-denatured, refolded, and incubated with diluted G-protein in human saliva matrix at 37 ◦ C for 15 min prior to injection
FAM-Gp-Apts incubated with HSA, anti-RSV-G IgG, RSV F, SARS-CoV-2 RBD, or H1N1 HA and analyzed by CE to calculate unbound aptamer peak area
5'-dGpdCpdCpdTpdTpdGpdApdTpdTpdTpdCpdApdCpdApdGpdGpdGpdTpdGpdTpdCpdCpdGpdCpdApdGpdGpdCpdApdGpdCpdTpdGpdCpdCpdApdTpdTpdApdGpdTpdCpdTpdCpdTpdApdTpdCpdCpdGpdTpdGpdApdCpdGpdGpdTpdApdTpdTpdTpdTpdGpdTpdTpdTpdTpdGpdGpdCpdGpdTpdTpdGpdTpdTpdTpdTpdGp-3'
91
28010.1 g/mole
862100 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Yang, G., Jiang, G., Lian, X., Cui, B., Wu, S., Wang, H., Yan, H., Wang, K., Gao, R., Qu, F., Jiang, J., & Li, Y. (2026). Aptamers targeting respiratory syncytial virus showed high inhibitory activity by blocking the G protein. Acta Pharmaceutica Sinica B, 16(3), 1762–1768. https://doi.org/10.1016/j.apsb.2025.12.027
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