Aptamer Details

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RGD motifs in Fibronectin and Vitronectin (ID# 7659)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
RGD motifs in Fibronectin and Vitronectin
N/A nM (reported value)
TBS Wash Buffer
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
This peptide aptamer may be cyclic because of the C- and N-terminal cysteine residues.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Pasqualini et al. "A Peptide Isolated from Phage Display Libraries Is a Structural and Functional Mimic of an RGD-binding Site on Integrins." The Journal of Cell Biology, 130(1995): 1189-1196.

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