Aptamer Details

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Prion Protein (ID# 7557)

Prion Protein
100 nM (reported value)
Binding Buffer (8um urea, 20 mm sodium phosphate, 500 mm sodium chloride (pH 7.8)) Selection Buffer (155 mM NaCl, 1.1 mM KH2PO4, 3.0 mM Na2HPO4, 1.0 mM MgCl2 (pH 7.4))
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Proske et al. "Prion-Protein-Specific Aptamer Reduces PrPSc Formation." Chem-Biochem, 3(2002): 717-725.

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