Aptamer Details

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Platelet-Derived Growth Factor (PDGF) B-chain (36t) (ID# 7545)

Platelet-Derived Growth Factor -AB (PDGF-AB)
0.094 nM (reported value)
Selection Buffer: PBSM(10.1 mM Na2HPO4, 1.8 mM K2HPO4, 137 mM NaCl and 2.7 mM KCl, 1 mM MgCl2 (pH 7.4))
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Contains a terminal 3'-3'-linked thymidine residue to protect from 3' exonuclease degradation.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Green, L., et al. "Inhibitory DNA Ligands to Platelet-Derived Growth Factor B-Chain." Journal of Biochemistry, 35(1996): 14413-14424.

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