Aptamer Details

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Peritoneal tumors of gastric cancer (ID# 7643)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peritoneal tumors of gastric cancer
N/A nM (reported value)
In vivo in mice. Washed with PBS containing 0.5% Tween-20 sorbitan monolaurate.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
KLP motif showed homology to laminin-5, which binds to a3??1 integrin, suggesting that this might be the target of the aptamer.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Akita et al. "Identification of oligopeptides binding to peritoneal tumors of gastric cancer." Japanese Cancer Association, 97(2006): 1075-1081.

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