Aptagen, LLC* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Peritoneal tumors of gastric cancer (ID# 7643)
Peritoneal tumors of gastric cancer
N/A nM (reported value)
In vivo in mice. Washed with PBS containing 0.5% Tween-20 sorbitan monolaurate.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
KLP motif showed homology to laminin-5, which binds to a3??1 integrin, suggesting that this might be the target of the aptamer.