Aptamer Details

Back to Search Results

NaA43 (ID# 7955)

Aptamer Chemistry: DNA

Target: Sodium Ion

Antigen/Target Category: Other

Affinity (Kd): 39.1 mM (reported value)

Binding Conditions/Buffer: Dulbeccoƒ??s modification of Eagleƒ??s medium (DMEM) supplemented with 10% Fetal Bovine Serum (FBS), 100 U/mL penicillin, and 100 µg/mL streptomycin,

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Tested against the following ions: Li, K, Rb, Cs, NH4, Mg, Ca, Sr, Ba, Mn, Co, Ni, Cu, Zn, Cd, Hg, Pb, In, La, Eu, Sm, Yb

Comments: SUBSTRATE SEQUENCE (spaces added before and after the ribonucleic A): dCpdTpdCpdTpdApdTpdGpdTpdApdTp rAp dGpdGpdApdApdGpdTpdApdCpdCpdGpdCpdCpdGpdCp

Sequence ():

Length: 61

Molecular Weight: 19035.35

Extinction Coefficient: 602700

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Torabi, S., Wu, P., McGhee, C., Chen, L., Hwang, K., Zheng, N., Cheng, J., & Lu, Y. (2015) In Vitro Selection of a Sodium-Specific DNAzyme and its Application in Intracellular Sensing. PNAS 112, (19):5903-5908

Have your aptamer oligo synthesized ORDER