Aptamer Details

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Mycolactone Aptamer (ID# 7972)

6.3 µM (reported value)
1X concentration (1X PBS [pH 7.4] and 10 mMMgCl2)
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
SpecificApta-3683 (0.5mM)mediated by the presence of mycolactone (100 mM) over a 3 minute time course was done

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Sakyi, Samuel A., et al. "RNA Aptamer That Specifically Binds to Mycolactone and Serves as a Diagnostic Tool for Diagnosis of Buruli Ulcer." PLOS Negl Trop Dis 10.10 (2016): e0004950 Miyakawa, Shin, et al. "Structural and molecular basis for hyperspecificity of RNA aptamer to human immunoglobulin G." RNA Journal 14,(2008): 1154-1163.

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