Aptamer Details

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Mouse Placenta (ID# 7638)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Neonatal Fc Receptor
N/A nM (reported value)
In vivo in pregnant mice.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Has been shown to interfere with the progression of pregnancy in mice.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Kolonin et al. "Teratogenicity induced by targeting a placental immunoglobulin transporter." PNAS, 99(2002): 13055-13060.

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