Aptamer Details

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Microcystin-LR (AN6) (ID# 7828)

Small Organic
50 nM (reported value)
Binding Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, and 2 mM MgCl2
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Binds to congener microcystin-LA with three-fold reduced affinity (Kd of 158). No binding observed to microcystin-YR.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Ng A, Zourob M, et al. (2012) Selection, characterization and biosensing application of high affinity congener-specific microcystin-targeting aptamers. Environ. Sci. Technol. 46: 10697-10703.

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