Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
L-Apt12-6 (ID# 9762)
L-RNA
c-kit 1 D-dG4
Other
42.3 ± 1.9 nM (reported value)
25 mM Tris-HCl (pH 7.5), 10 mM MgCl2, 150 mM KCl
37°C
Denature at 75°C for 3 min and cool down to room temperature
5'-LrCLrGLrCLrCLrGLrCLrCLrGLrGLrGLrULrALrULrGLrALrGLrGLrGLrALrGLrGLrALrGLrGLrGLrGLrGLrCLrGLrGLrCLrG-3'
32
10050.4 g/mole
308400 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Ji D, Yuan JH, Chen SB, Tan JH, Kwok CK. Selective targeting of parallel G-quadruplex structure using L-RNA aptamer. Nucleic Acids Res. 2023 Nov 27;51(21):11439-11452. doi: 10.1093/nar/gkad900. PMID: 37870474; PMCID: PMC10681708.
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