Aptagen, LLC
* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
L-Apt.8f (ID# 9767)
L-RNA
APP D-rG4
Other
24.06 ± 2.90 nM (reported value)
25 mM Tris-HCl (pH 8.0), 1 mM MgCl2, 150 mM KCl
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-LrGLrCLrGLrGLrCLrALrALrGLrALrGLrULrGLrULrGLrGLrGLrALrGLrGLrGLrGLrGLrGLrULrCLrGLrALrCLrGLrCLrCLrGLrC-3'
33
10324.6 g/mole
317500 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Novel L-RNA Aptamer Controls APP Gene Expression in Cells by Targeting RNA G-Quadruplex Structure Haizhou Zhao, Hei Yuen Wong, Danyang Ji, Kaixin Lyu, and Chun Kit Kwok ACS Applied Materials & Interfaces 2022 14 (27), 30582-30594 DOI: 10.1021/acsami.2c06390
Have your aptamer oligo synthesized ORDER
We are always looking for ways to improve. Please tell us what you think.