Aptamer Details

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Interleukin-17A/F (IL-17A/F) (APTAF42) (ID# 7525)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Human Interleukin-17A/F
72.2 nM (reported value)
Binding Buffer (145 mM sodium chloride, 5.4 mM potassium chloride, 0.8 mM magnesium chloride, 1.8 mM calcium chloride, 20 mM Trisƒ??HCl (pH 7.6) supplemented with 0.05% Tween20
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
See also the optimized version: AptAF42dope1.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Adachi, H., et al. "Antagonistic RNA aptamer specific to a heterodimeric form of human interleukin-17A/F." Biochemie, 93 (2011): 1081-1088.

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