Binding Buffer: 50 mM Tris-HCl, pH 7.5, 25 mM NaCl, 5 mM MgCl2.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
No binding observed with Influenza A/Panama and A/Aichi strains.
This aptamer inhibited HA-mediated membrane fusion in human red blood cell ghost membranes.