Aptamer Details

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Influenza B Hemagglutinin (A20) (ID# 7808)

Influenza B Hemagglutinin (HA)
720 pM (reported value)
Binding Buffer: 50 mM Tris-HCl, pH 7.5, 25 mM NaCl, 5 mM MgCl2.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
No binding observed with Influenza A/Panama and A/Aichi strains.
This aptamer inhibited HA-mediated membrane fusion in human red blood cell ghost membranes.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

S. Gopinath et al. An efficient RNA aptamer against human influenza B virus hemagglutinin. J. Biochem. 139(2006): 837-846.

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