Aptamer Details

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Human Gastric Adenocarcinoma (ID# 7656)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Human Gastric Adenocarcinoma
N/A nM (reported value)
In vivo in human tumor xenograft mice.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Only binds to the endothelial cells of human gastric adenocarcinoma blood vessels, not to blood vessels of human hepatocarcinoma, hemangioma, or normal spleen tissues.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Zhi et al. "Characterization of a Specific Phage-Displayed Peptide Binding to Vasculature of Human Gastric Cancer." Cancer Biology & Therapy, 3(2004): 1232-1235.

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