Aptamer Details

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GBN2 (ID# 8110)

Aptamer Chemistry: DNA

Target: Nervous necrosis virus (NNV)

Antigen/Target Category: Other

Affinity (Kd): 27.96 nM (reported value)

Binding Conditions/Buffer: 5 g/L glucose,10% FBS, 1.0 g/L bovine serum albumin, 0.1 mg/ml yeast tRNA and 5 mM MgCl2

Binding Temp: 4°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 95

Molecular Weight: 29267.9

Extinction Coefficient: 894300

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Zhou L, Wang S, Yu Q, et al. Characterization of Novel Aptamers Specifically Directed to Red-Spotted Grouper Nervous Necrosis Virus (RGNNV)-Infected Cells for Mediating Targeted siRNA Delivery. Front Microbiol. 2020;11:660. Published 2020 Apr 30. doi:10.3389/fmicb.2020.00660

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