FA1 Folate Aptamer Aptamer Details

FA1 Folate Aptamer (ID# 9951)

Aptamer Chemistry: DNA

Target: Folate

Antigen/Target Category: Small Organic

Affinity (Kd): 0.64 µM (reported value)

Binding Temp: 25°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Specifically binds to Folate, Tested against tetrahydrofolate and related fused N-heteroaromatic scaffolds, such as tetrahydrofolate, guanine, adenine, theophylline, xanthine, and caffeine

Sequence ():

Length: 42

Molecular Weight: 12856.3 g/mole

Extinction Coefficient: 389100 L/(mole·cm)

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Xie, Y., Chen, Y., & Liu, J. (2026). Capture-SELEX of DNA aptamers for highly selective binding of folate. SELEX Journal. Advance online publication.

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