Aptagen, LLC
ERK1/ ERK2 (Family II – Truncated) (ID# 7845)
RNA
Extracellular Regulated Kinase 1 and 2 (ERK 1 and ERK2)
Protein
N/A nM (reported value)
Buffer: 10 mM HEPES, pH 7.5; 10 mM MgCl2
30°C
Denatured in water at 95°C for 3 min and slowly cooling in binding buffer from 55°C to 30°C.
Binds to ERK 1/2 but not JNK or P38.
Truncated version of ERK 1/2 Family II apt
5'-rGprGprAp rAprAprGp rAprCprGp rCprUprAp rGprCprGp rAprAprUp rUprGprGp rUprUprCp rCprUprCp rGprAprAp rAprGprGp rGprGprAprAp rAprGprCp rGprUprUp rAprUprUp rAprAprGp rAprAprAp rCprCprAp rAprAprAp rUprUprUp rCprCp-3'
63
20370.42
651800
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Seiwert, S., et al. "RNA aptamers as pathway-specific MAP kinase inhibitors." Chemistry & Biology, 7(2000): 833-834.
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