Aptagen, LLC* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
ErbB2 Tyrosine Kinase Receptor (Ph-12-1) (ID# 7780)
ErbB2 Tyrosine Kinase Receptor
N/A nM (reported value)
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Binds strongly to breast cancer cell lines SKBR3, T47D, MCF-7, amd PM-1, prostate Du-145, Glioma U87MG, colon HT-2933, and lung DMS-273. Exhibits some binding to human lymphoblast lymphoma cell line K562.