Aptamer Details

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CTBA4T-B1 (ID# 8088)

19 pM (reported value)
Binding buffer (1× PBSMT, pH 7.2) containing 137 mM NaCl, 2.68 mM KCl, 8.1 mM Na2HPO4, 1.76 mM KH2PO4, 1 mM MgCl2, and 0.025% Tween-20.
95, 25°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Letters in yellow are nucleotides in the original central constant domain. Letters in blue are nucleotides in the two random-sequence regions. Those in red are nucleotides in the primer domains.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Mao, Yu et al. “Evolution of a highly functional circular DNA aptamer in serum.” Nucleic acids research vol. 48,19 (2020): 10680-10690. doi:10.1093/nar/gkaa800

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