Aptamer Details

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CoV2-6C3 (ID# 8195)

SARS-CoV-2 Spike Protein RBD
44.78 nM (reported value)
1X PBS, pH=7.4, including 136.8 mM NaCl, 10.1 mM Na2HPO4, 2.7 mM KCl, 1.8 mM KH2PO4, 0.55 mM MgCl2
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Recognizes baculovirus-insect-expressed RBD and HEK293-expressed RBD, as well as SARS-CoV-2 Spike proteinLow response to Spike protein from MERS-CoV, HCoV-HKU1, HIV-1 gp120

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Sun, M., Liu, S., Wei, X., Wan, S., Huang, M., Song, T., Lu, Y., Weng, X., Lin, Z., Chen, H., Song, Y., & Yang, C. (2021). Aptamer Blocking Strategy Inhibits SARS-CoV-2 Virus Infection. Angewandte Chemie (International ed. in English), 60(18), 10266–10272. https://doi.org/10.1002/anie.202100225

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