Aptamer Details

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Cocaine Aptamer (ID# 7966)

Aptamer Chemistry: DNA

Target: Cocaine

Antigen/Target Category: Small Organic

Affinity (Kd): N/A nM (reported value)

Binding Conditions/Buffer: The buffer for immobilization of ssDNA probe consisted of 0.8M phosphate buffer (PB) with 1.0M NaCl, 5 mM MgCl2 and 1 mM ethylenediamine tetraacetic acid (EDTA), pH 7.0. The DNA hybridization buffer and cocaine incubation buffer was composed of 50mM PB with 100mM K2SO4 (pH 7.4).

Binding Temp: 25°C

Refolding Protocol: N/A

Specificity: N/A

Sequence ():

Length: 43

Molecular Weight: 13274.72

Extinction Coefficient: 429800

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Yang, Z. et al. Community Sewage Sensors towards Evaluation of Drug Use Trends: Detection of Cocaine in Wastewater with DNA-Directed Immobilization Aptamer Sensors. Sci. Rep. 6, 21024; doi: 10.1038/srep21024 (2016).

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