Aptagen, LLC
CN-ES1 (17β-Estradiol) (ID# 9657)
DNA
17β-Estradiol
Small Organic
83 ± 25 nM (reported value)
SELEX Buffer: 20 mM Tris, pH 7.4, 500 mM NaCl, 10 mM MgCl2.
Sensing Buffer: 20 mM HEPES, pH 7.4, 100 mM NaCl, 10 mM MgCl2
Room Temperature°C
Heated to unspecified temperature for annealing, allowed to cool to room temperature.
Somewhat more selective for 17β-Estradiol than for related estrogens estrone or 17α-ethynylestradiol. It appears to bind them in a shared region and can therefore detect them as a group. Shows no response to cortisol, deoxycholic acid, thymidine, and dopamine.
dApdCpdGpdApdCpdGpdGpdTpdGpdGpdCpdApdTpdGpdApdApdCpdApdTpdApdApdGpdTpdTpdCpdCpdCpdCpdCpdTpdTpdGpdApdApdApdGpdTpdCpdGpdTp
40
12305 g/mole
389000 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Capture-SELEX of DNA Aptamers for Estradiol Specifically and Estrogenic Compounds Collectively Chenqi Niu, Chong Zhang, and Juewen Liu Environmental Science & Technology 2022 56 (24), 17702-17711 DOI: 10.1021/acs.est.2c05808
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