Aptagen, LLC
Chlorpromazine (CHL-3) (ID# 10031)
DNA
chlorpromazine
Other
69.8 ± 9.81 nM (reported value)
50 mM Tris-HCl, 5 mM KCl, 100 mM NaCl, 1 mM MgCl2, pH 7.4
37°C
Heated for 10 min at 95°C, cooled at room temperature over 10 min, incubated at 37°C for 1 hour
Specifically binds to chlorpromazine over azaperzone, haloperidol, promethazine, and acetpromazine
5'-dTpdCpdGpdGpdApdGpdGpdGpdApdApdGpdTpdGpdCpdApdCpdCpdCpdApdTpdTpdCpdTpdTpdGpdGpdApdApdApdCpdApdGpdGpdApdGpdCpdTpdCpdCpdTpdGpdApdApdCpdCpdGpdCpdCpdCpdApdCpdApdCpdGpdCp-3'
55
16900 g/mole
520400 L/(mole·cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Mingqian Song, Changxin Li, Shijia Wu, Nuo Duan, Screening of specific aptamers against chlorpromazine and construction of novel ratiometric fluorescent aptasensor based on metal-organic framework, Talanta, Volume 252, 2023, 123850, ISSN 0039-9140, https://doi.org/10.1016/j.talanta.2022.123850.
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