Aptamer Details

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Cellobiose (Cel#16) (ID# 7497)

Small Organic
600 nM (reported value)
Binding buffer: 20 mM Tris (pH 7.5), 100 mM NaCl, 5 mM MgCl2
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Binds to cellobiose, but not to related disaccharides lactose, maltose, or gentiobiose.
Other selected clones tended to also be G-rich, with the total pool possessing 50-60% G content.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Yang, Q., et al. "DNA ligands that bind tightly and selectively to cellobiose." PNAS, 95 (1998): 5462-5467.

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