Aptamer Details

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C5s Anti-Antibody (ID# 7959)

Aptamer Chemistry: DNA

Target: Anti-Vesicular Stomatitis Antibody

Antigen/Target Category: Antibody

Affinity (Kd): n/a nM (reported value)

Binding Conditions/Buffer: 90% High Glucose DMEM, 10% Fetal Bovine Serum. Tested in vivo.

Binding Temp: 37°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 40

Molecular Weight: 12587.16

Extinction Coefficient: 385000

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Muharemagic D, Zamay A, Ghobadloo SM, Evgin L, Savitskaya A, et al. (2014) Aptamer-Facilitated Protection of Oncolytic Virus from Neutralizing Antibodies. Molecular Therapy--Nucleic Acids 3, e167. doi: 10.1038/mtna.2014.19

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