Aptamer Details

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Brain-homing peptide (PEPC7) (ID# 7697)

* The secondary structure may not be accurate because of MFOLD limitations on chemistries other than RNA/DNA.
Murine Brain
N/A nM (reported value)
Selection and in vivo imaging performed in mice.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
This peptide is capable of penetrating the blood brain barrier and ushering through the attached bacteriophage.

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Jingwei, L. Identification of peptide sequences that target to the brain using in vivo phage display. Amino Acids, 2012(42), 2373-2381. doi: 10.1007/s00726-011-0979-y

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