Aptagen, LLC
Aptamer TY04 (ID# 7938)
DNA
Multiple myeloma cells (MM.1S)
Cells
3.89 µM (reported value)
yeast tRNA (0.1mg/ml; Sigma) and BSA (1 mg/ml; Sigma) into the wash buffer
37°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Aptermer TY04 inhibits the growth of MM cell lines, including MM.1S, NCI-H929, KM3, and OPM2.
5'-dApdTpdCpdGpdTpdCpdTpdGpdCpdTpdCpdCpdGpdTpdCpdCpdApdApdTpdApdTpdApdTpdCpdApdApdApdGpdGpdCpdGpdApdApdTpdTpdTpdTpdGpdTpdCpdApdApdGpdGpdTpdGpdTpdTpdApdApdApdCpdGpdApdTpdApdGpdTpdCpdCpdCpdTpdApdCpdCpdTpdTpdTpdGpdGpdTpdGpdTpdGpdApdGpdGpdTpdCpdGpdTpdGpdCp-3'
83
25587.67
794400
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Dai, H. et al. "Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest." Tumor Biology 2014: 1-8.
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