Aptagen, LLC
Aptamer MN711 against Neurofilament Light Chain (NfL) – Alzheimer’s disease (ID# 9940)
DNA
Neurofilament Light Chain (NfL) - Alzheimer's disease
Protein
11 nM (reported value)
Binding activity was detected separately in both 1X PBS and donor human plasma.
25°C
In 1X PBS: heated at 95C for 10 minutes, gradually cooled to 25C over 30 min.
No binding to NfL381-543
Specific G-quadruplex structure may differ from placeholder image.
5'-dGpdGpdTpdGpdGpdTpdGpdTpdGpdGpdTpdGpdGpdGpdTpdGpdGpdGpdTpdTpdGpdTpdCpdTpdGpdTpdGpdTpdGpdGp-3'
30
9499.1 g/mole
284,900 L/(mole*cm)
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Matsumoto, M., Ikebukuro, K., Tsukakoshi, K., 2026. Competitive-selex discovery of DNA aptamers selective for neurofilament light chain in human plasma. Biochemical and Biophysical Research Communications 796, 153151. doi:10.1016/j.bbrc.2025.153151
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