Aptamer Details

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Apta 3 (ID# 8123)

Carcinoembryonic antigen (CEA)
60.4 nM (reported value)
Not given.
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
Apta 3 displayed high specificity and affinity for T84 cells (human carcinoma cell line derived from a lung metastasis of a colon carcinoma).

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Melo, M.; Correa, C.; Cunha, P.; Goes, A.; Gomes, D.; Andrade, A. DNA aptamers selection for carcinoembryonic antigen (CEA). Bioorg. Med. Chem. Lett. 2020 May 23; 30(15): 127278. DOI: 10.1016/j.bmcl.2020.127278

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