Apt-E1(Erythromycin-Resistant Methyltransferase (Erm) Aptamer Details

Apt-E1(Erythromycin-Resistant Methyltransferase (Erm) (ID# 9927)

Aptamer Chemistry: DNA

Target: Erythromycin-Resistant Methyltransferase (Erm 42)

Antigen/Target Category: Small Organic

Affinity (Kd): 7.8 nM (reported value)

Binding Temp: 79.1°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Specificity: Not specific for other nonmethyltransferase proteins such as EmtA. EfmM, RmtB, ArmA.

Sequence ():

Length: 73

Molecular Weight: 22659.7 g/mole

Extinction Coefficient: 698600 L/(mole·cm)

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Leena Laxmikant Badgujar, Damini Sahu, Ruchi Anand, and P. I. Pradeepkumar ACS Infectious Diseases 2026 12 (1), 212-223 DOI: 10.1021/acsinfecdis.5c00756

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