Aptagen, LLC
Apt-3 (ID# 8116)
DNA
C promoter binding factor 1 (CBF1)
Protein
34 nM (reported value)
100 mM Tris-HCl (pH 8.0), 100 mM NaCl, 5 mM KCl, 1 mM MgCl2, 0.1% Tween 20, 1 mg/mL BSA
22°C
NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.
5'-dApdTpdApdGpdGpdApdGpdTpdCpdGpdApdCpdCpdGpdApdCpdCpdApdGpdApdCpdCpdApdApdCpdCpdCpdTpdApdCpdGpdCpdGpdTpdApdCpdCpdApdAp dCpdCpdApdGpdApdTpdGpdApdCpdCpdTpdApdCpdGpdTpdGpdCpdGpdTpdCpdTpdApdCpdApdTpdCpdTpdApdGpdApdCpdTpdCp
-3'
72
22004.3
693600
Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Tezuka-Kagajo, Mari et al. “Development of Human CBF1-Targeting Single-Stranded DNA Aptamers with Antiangiogenic Activity In Vitro.” Nucleic acid therapeutics vol. 30,6 (2020): 365-378. doi:10.1089/nat.2020.0875
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