Aptamer Details

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Apt-07S (ID# 8108)

Aptamer Chemistry: DNA

Target: HepG2 (Kd = 194.7nM) and SMMC-7721 (Kd = 224.2nM)

Antigen/Target Category: Cells

Affinity (Kd): 194.7 and 224.2 nM (reported value)

Binding Conditions/Buffer: 1×PBS–1 mM MgCl2–0.1 μg/μL ytRNA–0.1 μg/μL wDNA–X pmol ssDNA library.

Binding Temp: 4°C

Refolding Protocol: NA If the oligo is a known aptamer sequence: For binding studies, perform a refolding protocol to ensure proper function (i.e. binding to antigen or target). Refer to the aptamer reference source for the appropriate refolding parameters and binding conditions. Note: it is unknown whether aptamer functions properly without refolding.

Sequence ():

Length: 47

Molecular Weight: 14594.5

Extinction Coefficient: 462500

Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.

Reference:

Yu XX, Ge KL, Liu N, Zhang JY, Xue ML, Ge YL. Selection and Characterization of a Novel DNA Aptamer, Apt-07S Specific to Hepatocellular Carcinoma Cells. Drug Des Devel Ther. 2020 Apr 20;14:1535-1545. doi: 10.2147/DDDT.S244149. PMID: 32368012; PMCID: PMC7182459.

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