Aptagen, LLC
            
                
                    
                                                    
                                            
                                    
                
                                            
            
            
            
            
        
    #97 (ID# 8849)
                                            
                            
                            DNA
                        
                    
                                            
                            
                            Hamster prion protein (Sequence 90-231)
                        
                    
                                            
                            
                            Protein
                        
                    
                                            
                            
                            1-10 nM (reported value)
                        
                    
                                            
                            
                            1X Selection buffer (SB)
                        
                    
                    
                    
                        
                        
                                                            Heated to 100°C for 5 min in 1XSB; Cooled to RT                                                    
                    
                    
                                            
                            
                            Room temperature not specified; presumed to be 23°C
                        
                                    
                
                
                    5'-dTsdGsdCsdTsdGsdCsdGsdGsdTsdTsdCsdGsdAsdCsdAsdCsdAsdAsdGsdCsdCsdGsdAsdGsdCsdGsdTsdTsdTsdAsdGsdGsdCsdTsdAsdCsdGsdGsdTsdAs-3'
                
                
                    
                
                                    
                        
                        
                            Mollasalehi N., Francois-Moutal L., Porciani D., Burke D.H., & Khanna M. (2022). Aptamers Targeting Hallmark Proteins of Neurodegeneration. Nucleic Acid Therapeutics, 32(4). https://doi.org/10.1089/nat.2021.0091 
                        
                    
                
                
                
            
            
        
                
                        
                        40
                    
                
                                    
                        
                        12353
                    
                            
                                    
                        
                        380500
                    
                            
                
                
                Note: Information on this aptamer oligo was obtained from the literature and hasn't been validated by Aptagen.
Mollasalehi N., Francois-Moutal L., Porciani D., Burke D.H., & Khanna M. (2022). Aptamers Targeting Hallmark Proteins of Neurodegeneration. Nucleic Acid Therapeutics, 32(4). https://doi.org/10.1089/nat.2021.0091 
Kind D.J., Safar J.G., Legname G., & Prusiner S.B. (2007). Thioaptamer Interactions with Prion Proteins: Sequence-specific and Non-specific Binding Sites. Journal of Molecular Biology, 369(4), 1001-1014. https://doi.org/10.1016/j.jmb.2007.02.004
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